Human CLOCK(Circadian Locomoter Output Cycles Protein Kaput) ELISA Kit

Human CLOCK(Circadian Locomoter Output Cycles Protein Kaput) ELISA Kit

Circadian Locomoter Output Cycles Protein Kaput (CLOCK) Antibody

abx231769-100ug Abbexa 100 ug 481 EUR

Circadian Locomoter Output Cycles Protein Kaput (CLOCK) Antibody

20-abx328613 Abbexa
  • 314.00 EUR
  • 244.00 EUR
  • 100 ug
  • 50 ug

Human Circadian Locomoter Output Cycles Protein Kaput ELISA Kit (CLOCK)

RK01134 Abclonal 96 Tests 521 EUR

Human Circadian Locomoter Output Cycles Protein Kaput (CLOCK) ELISA Kit

SEQ116Hu-10x96wellstestplate Cloud-Clone 10x96-wells test plate 5189.65 EUR
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Circadian Locomoter Output Cycles Protein Kaput (CLOCK) in tissue homogenates, cell lysates and other biological fluids.

Human Circadian Locomoter Output Cycles Protein Kaput (CLOCK) ELISA Kit

SEQ116Hu-1x48wellstestplate Cloud-Clone 1x48-wells test plate 515.03 EUR
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Circadian Locomoter Output Cycles Protein Kaput (CLOCK) in tissue homogenates, cell lysates and other biological fluids.

Human Circadian Locomoter Output Cycles Protein Kaput (CLOCK) ELISA Kit

SEQ116Hu-1x96wellstestplate Cloud-Clone 1x96-wells test plate 692.9 EUR
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Circadian Locomoter Output Cycles Protein Kaput (CLOCK) in tissue homogenates, cell lysates and other biological fluids.

Human Circadian Locomoter Output Cycles Protein Kaput (CLOCK) ELISA Kit

SEQ116Hu-5x96wellstestplate Cloud-Clone 5x96-wells test plate 2818.05 EUR
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Circadian Locomoter Output Cycles Protein Kaput (CLOCK) in tissue homogenates, cell lysates and other biological fluids.

Human Circadian Locomoter Output Cycles Protein Kaput (CLOCK) ELISA Kit

4-SEQ116Hu Cloud-Clone
  • 5240.00 EUR
  • 2769.00 EUR
  • 693.00 EUR
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Circadian Locomoter Output Cycles Protein Kaput (CLOCK) in samples from tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.

Human Circadian locomoter output cycles protein kaput(CLOCK) ELISA kit

E01C1807-192T BlueGene 192 tests 1270 EUR
Description: A sandwich ELISA for quantitative measurement of Human Circadian locomoter output cycles protein kaput(CLOCK) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Circadian locomoter output cycles protein kaput(CLOCK) ELISA kit

E01C1807-48 BlueGene 1 plate of 48 wells 520 EUR
Description: A sandwich ELISA for quantitative measurement of Human Circadian locomoter output cycles protein kaput(CLOCK) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Circadian locomoter output cycles protein kaput(CLOCK) ELISA kit

E01C1807-96 BlueGene 1 plate of 96 wells 685 EUR
Description: A sandwich ELISA for quantitative measurement of Human Circadian locomoter output cycles protein kaput(CLOCK) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Circadian Locomoter Output Cycles Protein Kaput (CLOCK) Antibody (HRP)

20-abx316830 Abbexa
  • 411.00 EUR
  • 1845.00 EUR
  • 599.00 EUR
  • 182.00 EUR
  • 300.00 EUR
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Circadian Locomoter Output Cycles Protein Kaput (CLOCK) Antibody (FITC)

20-abx316831 Abbexa
  • 411.00 EUR
  • 1845.00 EUR
  • 599.00 EUR
  • 182.00 EUR
  • 300.00 EUR
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Circadian Locomoter Output Cycles Protein Kaput (CLOCK) Antibody (Biotin)

20-abx316832 Abbexa
  • 411.00 EUR
  • 1845.00 EUR
  • 599.00 EUR
  • 182.00 EUR
  • 300.00 EUR
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Mouse Circadian Locomoter Output Cycles Protein Kaput (CLOCK) ELISA Kit

20-abx258674 Abbexa
  • 7504.00 EUR
  • 3996.00 EUR
  • 926.00 EUR
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Mouse Circadian Locomoter Output Cycles Protein Kaput (CLOCK) ELISA Kit

SEQ116Mu-10x96wellstestplate Cloud-Clone 10x96-wells test plate 5333.64 EUR
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Circadian Locomoter Output Cycles Protein Kaput (CLOCK) in Tissue homogenates, cell lysates and other biological fluids.

Mouse Circadian Locomoter Output Cycles Protein Kaput (CLOCK) ELISA Kit

SEQ116Mu-1x48wellstestplate Cloud-Clone 1x48-wells test plate 526.89 EUR
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Circadian Locomoter Output Cycles Protein Kaput (CLOCK) in Tissue homogenates, cell lysates and other biological fluids.

Mouse Circadian Locomoter Output Cycles Protein Kaput (CLOCK) ELISA Kit

SEQ116Mu-1x96wellstestplate Cloud-Clone 1x96-wells test plate 709.84 EUR
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Circadian Locomoter Output Cycles Protein Kaput (CLOCK) in Tissue homogenates, cell lysates and other biological fluids.

Mouse Circadian Locomoter Output Cycles Protein Kaput (CLOCK) ELISA Kit

SEQ116Mu-5x96wellstestplate Cloud-Clone 5x96-wells test plate 2894.28 EUR
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Circadian Locomoter Output Cycles Protein Kaput (CLOCK) in Tissue homogenates, cell lysates and other biological fluids.

Mouse Circadian Locomoter Output Cycles Protein Kaput (CLOCK) ELISA Kit

4-SEQ116Mu Cloud-Clone
  • 5384.00 EUR
  • 2845.00 EUR
  • 710.00 EUR
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Circadian Locomoter Output Cycles Protein Kaput (CLOCK) in samples from Tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.

Dog Circadian locomoter output cycles protein kaput(CLOCK) ELISA kit

E08C1807-192T BlueGene 192 tests 1270 EUR
Description: A sandwich ELISA for quantitative measurement of Canine Circadian locomoter output cycles protein kaput(CLOCK) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Circadian locomoter output cycles protein kaput(CLOCK) ELISA kit

E08C1807-48 BlueGene 1 plate of 48 wells 520 EUR
Description: A sandwich ELISA for quantitative measurement of Canine Circadian locomoter output cycles protein kaput(CLOCK) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Circadian locomoter output cycles protein kaput(CLOCK) ELISA kit

E08C1807-96 BlueGene 1 plate of 96 wells 685 EUR
Description: A sandwich ELISA for quantitative measurement of Canine Circadian locomoter output cycles protein kaput(CLOCK) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Circadian locomoter output cycles protein kaput(CLOCK) ELISA kit

E06C1807-192T BlueGene 192 tests 1270 EUR
Description: A sandwich ELISA for quantitative measurement of Goat Circadian locomoter output cycles protein kaput(CLOCK) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Circadian locomoter output cycles protein kaput(CLOCK) ELISA kit

E06C1807-48 BlueGene 1 plate of 48 wells 520 EUR
Description: A sandwich ELISA for quantitative measurement of Goat Circadian locomoter output cycles protein kaput(CLOCK) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Circadian locomoter output cycles protein kaput(CLOCK) ELISA kit

E06C1807-96 BlueGene 1 plate of 96 wells 685 EUR
Description: A sandwich ELISA for quantitative measurement of Goat Circadian locomoter output cycles protein kaput(CLOCK) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Circadian locomoter output cycles protein kaput(CLOCK) ELISA kit

E04C1807-192T BlueGene 192 tests 1270 EUR
Description: A sandwich ELISA for quantitative measurement of Rabbit Circadian locomoter output cycles protein kaput(CLOCK) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Circadian locomoter output cycles protein kaput(CLOCK) ELISA kit

E04C1807-48 BlueGene 1 plate of 48 wells 520 EUR
Description: A sandwich ELISA for quantitative measurement of Rabbit Circadian locomoter output cycles protein kaput(CLOCK) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Circadian locomoter output cycles protein kaput(CLOCK) ELISA kit

E04C1807-96 BlueGene 1 plate of 96 wells 685 EUR
Description: A sandwich ELISA for quantitative measurement of Rabbit Circadian locomoter output cycles protein kaput(CLOCK) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Circadian locomoter output cycles protein kaput(CLOCK) ELISA kit

E03C1807-192T BlueGene 192 tests 1270 EUR
Description: A sandwich ELISA for quantitative measurement of Mouse Circadian locomoter output cycles protein kaput(CLOCK) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Circadian locomoter output cycles protein kaput(CLOCK) ELISA kit

E03C1807-48 BlueGene 1 plate of 48 wells 520 EUR
Description: A sandwich ELISA for quantitative measurement of Mouse Circadian locomoter output cycles protein kaput(CLOCK) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Circadian locomoter output cycles protein kaput(CLOCK) ELISA kit

E03C1807-96 BlueGene 1 plate of 96 wells 685 EUR
Description: A sandwich ELISA for quantitative measurement of Mouse Circadian locomoter output cycles protein kaput(CLOCK) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Circadian locomoter output cycles protein kaput(CLOCK) ELISA kit

E07C1807-192T BlueGene 192 tests 1270 EUR
Description: A sandwich ELISA for quantitative measurement of Porcine Circadian locomoter output cycles protein kaput(CLOCK) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Circadian locomoter output cycles protein kaput(CLOCK) ELISA kit

E07C1807-48 BlueGene 1 plate of 48 wells 520 EUR
Description: A sandwich ELISA for quantitative measurement of Porcine Circadian locomoter output cycles protein kaput(CLOCK) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Circadian locomoter output cycles protein kaput(CLOCK) ELISA kit

E07C1807-96 BlueGene 1 plate of 96 wells 685 EUR
Description: A sandwich ELISA for quantitative measurement of Porcine Circadian locomoter output cycles protein kaput(CLOCK) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Circadian locomoter output cycles protein kaput(CLOCK) ELISA kit

E02C1807-192T BlueGene 192 tests 1270 EUR
Description: A sandwich ELISA for quantitative measurement of Rat Circadian locomoter output cycles protein kaput(CLOCK) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Circadian locomoter output cycles protein kaput(CLOCK) ELISA kit

E02C1807-48 BlueGene 1 plate of 48 wells 520 EUR
Description: A sandwich ELISA for quantitative measurement of Rat Circadian locomoter output cycles protein kaput(CLOCK) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Circadian locomoter output cycles protein kaput(CLOCK) ELISA kit

E02C1807-96 BlueGene 1 plate of 96 wells 685 EUR
Description: A sandwich ELISA for quantitative measurement of Rat Circadian locomoter output cycles protein kaput(CLOCK) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Circadian locomoter output cycles protein kaput(CLOCK) ELISA kit

E09C1807-192T BlueGene 192 tests 1270 EUR
Description: A sandwich ELISA for quantitative measurement of Monkey Circadian locomoter output cycles protein kaput(CLOCK) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Circadian locomoter output cycles protein kaput(CLOCK) ELISA kit

E09C1807-48 BlueGene 1 plate of 48 wells 520 EUR
Description: A sandwich ELISA for quantitative measurement of Monkey Circadian locomoter output cycles protein kaput(CLOCK) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Circadian locomoter output cycles protein kaput(CLOCK) ELISA kit

E09C1807-96 BlueGene 1 plate of 96 wells 685 EUR
Description: A sandwich ELISA for quantitative measurement of Monkey Circadian locomoter output cycles protein kaput(CLOCK) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Circadian Locomoter Output Cycles Protein Kaput (CLOCK) CLIA Kit

20-abx496160 Abbexa
  • 8569.00 EUR
  • 4560.00 EUR
  • 1052.00 EUR
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

ELISA kit for Human CLOCK (Circadian Locomoter Output Cycles Protein Kaput)

ELK6572 ELK Biotech 1 plate of 96 wells 432 EUR
Description: A sandwich ELISA kit for detection of Circadian Locomoter Output Cycles Protein Kaput from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

ELISA kit for Mouse CLOCK (Circadian Locomoter Output Cycles Protein Kaput)

ELK8166 ELK Biotech 1 plate of 96 wells 432 EUR
Description: A sandwich ELISA kit for detection of Circadian Locomoter Output Cycles Protein Kaput from Mouse in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Guinea pig Circadian locomoter output cycles protein kaput(CLOCK) ELISA kit

E05C1807-192T BlueGene 192 tests 1270 EUR
Description: A sandwich ELISA for quantitative measurement of Guinea pig Circadian locomoter output cycles protein kaput(CLOCK) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Circadian locomoter output cycles protein kaput(CLOCK) ELISA kit

E05C1807-48 BlueGene 1 plate of 48 wells 520 EUR
Description: A sandwich ELISA for quantitative measurement of Guinea pig Circadian locomoter output cycles protein kaput(CLOCK) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Circadian locomoter output cycles protein kaput(CLOCK) ELISA kit

E05C1807-96 BlueGene 1 plate of 96 wells 685 EUR
Description: A sandwich ELISA for quantitative measurement of Guinea pig Circadian locomoter output cycles protein kaput(CLOCK) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Clock Homolog (CLOCK) ELISA Kit

DLR-CLOCK-Hu-48T DL Develop 48T 554 EUR
Description: A sandwich quantitative ELISA assay kit for detection of Human Clock Homolog (CLOCK) in samples from tissue homogenates, cell lysates or other biological fluids.

Human Clock Homolog (CLOCK) ELISA Kit

DLR-CLOCK-Hu-96T DL Develop 96T 725 EUR
Description: A sandwich quantitative ELISA assay kit for detection of Human Clock Homolog (CLOCK) in samples from tissue homogenates, cell lysates or other biological fluids.

Human Clock Homolog (CLOCK) ELISA Kit

RD-CLOCK-Hu-48Tests Reddot Biotech 48 Tests 563 EUR

Human Clock Homolog (CLOCK) ELISA Kit

RD-CLOCK-Hu-96Tests Reddot Biotech 96 Tests 783 EUR

Human Clock Homolog (CLOCK) ELISA Kit

RDR-CLOCK-Hu-48Tests Reddot Biotech 48 Tests 589 EUR

Human Clock Homolog (CLOCK) ELISA Kit

RDR-CLOCK-Hu-96Tests Reddot Biotech 96 Tests 820 EUR

Circadian Clock Protein PASD1 (PASD1) Antibody

20-abx302666 Abbexa
  • 411.00 EUR
  • 1845.00 EUR
  • 599.00 EUR
  • 182.00 EUR
  • 300.00 EUR
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Circadian Clock Protein PASD1 (PASD1) Antibody

abx030966-400ul Abbexa 400 ul 523 EUR

Circadian Clock Protein PASD1 (PASD1) Antibody

abx030966-80l Abbexa 80 µl 286 EUR

Circadian Clock Protein PASD1 (PASD1) Antibody

abx340216-100ug Abbexa 100 ug 391 EUR

Human Clock Homolog (CLOCK)ELISA Kit

201-12-2901 SunredBio 96 tests 440 EUR
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Clock Homolog (CLOCK) ELISA Kit

20-abx151098 Abbexa
  • 7378.00 EUR
  • 3933.00 EUR
  • 911.00 EUR
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Clock Homolog(CLOCK)ELISA Kit

QY-E05041 Qayee Biotechnology 96T 361 EUR

Clock/ Rat Clock ELISA Kit

ELI-50992r Lifescience Market 96 Tests 886 EUR

Human Clock Homolog (CLOCK) Protein

20-abx650822 Abbexa
  • 634.00 EUR
  • 272.00 EUR
  • 1929.00 EUR
  • 759.00 EUR
  • 467.00 EUR
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human CLOCK ELISA KIT

ELI-50183h Lifescience Market 96 Tests 824 EUR

CLOCK ELISA KIT|Human

EF008732 Lifescience Market 96 Tests 689 EUR

Human Clock Homolog (CLOCK) CLIA Kit

20-abx496159 Abbexa
  • 8569.00 EUR
  • 4560.00 EUR
  • 1052.00 EUR
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

CLOCK ELISA Kit (Human) (OKCD01088)

OKCD01088 Aviva Systems Biology 96 Wells 909 EUR
Description: Description of target: Transcriptional activator which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. It is derived from the Latin roots 'circa' (about) and 'diem' (day) and acts as an important regulator of a wide array of physiological functions including metabolism, sleep, body temperature, blood pressure, endocrine, immune, cardiovascular, and renal function. Consists of two major components: the central clock, residing in the suprachiasmatic nucleus (SCN) of the brain, and the peripheral clocks that are present in nearly every tissue and organ system. Both the central and peripheral clocks can be reset by environmental cues, also known as Zeitgebers (German for 'timegivers'). The predominant Zeitgeber for the central clock is light, which is sensed by retina and signals directly to the SCN. The central clock entrains the peripheral clocks through neuronal and hormonal signals, body temperature and feeding-related cues, aligning all clocks with the external light/dark cycle. Circadian rhythms allow an organism to achieve temporal homeostasis with its environment at the molecular level by regulating gene expression to create a peak of protein expression once every 24 hours to control when a particular physiological process is most active with respect to the solar day. Transcription and translation of core clock components (CLOCK, NPAS2, ARNTL/BMAL1, ARNTL2/BMAL2, PER1, PER2, PER3, CRY1 and CRY2) plays a critical role in rhythm generation, whereas delays imposed by post-translational modifications (PTMs) are important for determining the period (tau) of the rhythms (tau refers to the period of a rhythm and is the length, in time, of one complete cycle). A diurnal rhythm is synchronized with the day/night cycle, while the ultradian and infradian rhythms have a period shorter and longer than 24 hours, respectively. Disruptions in the circadian rhythms contribute to the pathology of cardiovascular diseases, cancer, metabolic syndromes and aging. A transcription/translation feedback loop (TTFL) forms the core of the molecular circadian clock mechanism. Transcription factors, CLOCK or NPAS2 and ARNTL/BMAL1 or ARNTL2/BMAL2, form the positive limb of the feedback loop, act in the form of a heterodimer and activate the transcription of core clock genes and clock-controlled genes (involved in key metabolic processes), harboring E-box elements (5'-CACGTG-3') within their promoters. The core clock genes: PER1/2/3 and CRY1/2 which are transcriptional repressors form the negative limb of the feedback loop and interact with the CLOCK|NPAS2-ARNTL/BMAL1|ARNTL2/BMAL2 heterodimer inhibiting its activity and thereby negatively regulating their own expression. This heterodimer also activates nuclear receptors NR1D1/2 and RORA/B/G, which form a second feedback loop and which activate and repress ARNTL/BMAL1 transcription, respectively. CLOCK has an intrinsic acetyltransferase activity, which enables circadian chromatin remodeling by acetylating histones and nonhistone proteins, including its own partner ARNTL/BMAL1. Regulates the circadian expression of ICAM1, VCAM1, CCL2, THPO and MPL and also acts as an enhancer of the transactivation potential of NF-kappaB. Plays an important role in the homeostatic regulation of sleep. The CLOCK-ARNTL/BMAL1 heterodimer regulates the circadian expression of SERPINE1/PAI1, VWF, B3, CCRN4L/NOC, NAMPT, DBP, MYOD1, PPARGC1A, PPARGC1B, SIRT1, GYS2, F7, NGFR, GNRHR, BHLHE40/DEC1, ATF4, MTA1, KLF10 and also genes implicated in glucose and lipid metabolism. Represses glucocorticoid receptor NR3C1/GR-induced transcriptional activity by reducing the association of NR3C1/GR to glucocorticoid response elements (GREs) via the acetylation of multiple lysine residues located in its hinge region. Promotes rhythmic chromatin opening, regulating the DNA accessibility of other transcription factors. The CLOCK-ARNTL2/BMAL2 heterodimer activates the transcription of SERPINE1/PAI1 and BHLHE40/DEC1.7 Publications <p>Manually curated information for which there is published experimental evidence.</p> <p><a href="/manual/evidences#ECO:0000269">More…</a></p> Manual assertion based on experiment iniRef.8"Histone acetyltransferase-dependent chromatin remodeling and the vascular clock."_x005F_x005F_x000D_Curtis A.M., Seo S.B., Westgate E.J., Rudic R.D., Smyth E.M., Chakravarti D., FitzGerald G.A., McNamara P._x005F_x005F_x000D_J. Biol. Chem. 279:7091-7097(2004) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION, SUBCELLULAR LOCATION, INTERACTION WITH KAT2B; CREBBP AND EP300.Ref.10"CLOCK/BMAL1 regulates human nocturnin transcription through binding to the E-box of nocturnin promoter."_x005F_x005F_x000D_Li R., Yue J., Zhang Y., Zhou L., Hao W., Yuan J., Qiang B., Ding J.M., Peng X., Cao J.M._x005F_x005F_x000D_Mol. Cell. Biochem. 317:169-177(2008) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION.Ref.13"Peripheral CLOCK regulates target-tissue glucocorticoid receptor transcriptional activity in a circadian fashion in man."_x005F_x005F_x000D_Charmandari E., Chrousos G.P., Lambrou G.I., Pavlaki A., Koide H., Ng S.S., Kino T._x005F_x005F_x000D_PLoS ONE 6:E25612-E25612(2011) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION, INTERACTION WITH NR3C1.Ref.14"A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signaling."_x005F_x005F_x000D_Cotta-Ramusino C., McDonald E.R. III, Hurov K., Sowa M.E., Harper J.W., Elledge S.J._x005F_x005F_x000D_Science 332:1313-1317(2011) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION, SUBCELLULAR LOCATION.Ref.16"Diurnal expression of the thrombopoietin gene is regulated by CLOCK."_x005F_x005F_x000D_Tracey C.J., Pan X., Catterson J.H., Harmar A.J., Hussain M.M., Hartley P.S._x005F_x005F_x000D_J. Thromb. Haemost. 10:662-669(2012) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION.Ref.19"p75 neurotrophin receptor is a clock gene that regulates oscillatory components of circadian and metabolic networks."_x005F_x005F_x000D_Baeza-Raja B., Eckel-Mahan K., Zhang L., Vagena E., Tsigelny I.F., Sassone-Corsi P., Ptacek L.J., Akassoglou K._x005F_x005F_x000D_J. Neurosci. 33:10221-10234(2013) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION.Ref.22"A meeting of two chronobiological systems: circadian proteins Period1 and BMAL1 modulate the human hair cycle clock."_x005F_x005F_x000D_Al-Nuaimi Y., Hardman J.A., Biro T., Haslam I.S., Philpott M.P., Toth B.I., Farjo N., Farjo B., Baier G., Watson R.E., Grimaldi B., Kloepper J.E., Paus R._x005F_x005F_x000D_J. Invest. Dermatol. 134:610-619(2014) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION, TISSUE SPECIFICITY. ;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: < 0.117 ng/mL

CLOCK ELISA Kit (Human) (OKAN04742)

OKAN04742 Aviva Systems Biology 96 Wells 792 EUR
Description: Description of target: The protein encoded by this gene plays a central role in the regulation of circadian rhythms. The protein encodes a transcription factor of the basic helix-loop-helix (bHLH) family and contains DNA binding histone acetyltransferase activity. The encoded protein forms a heterodimer with ARNTL (BMAL1) that binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Polymorphisms in this gene may be associated with behavioral changes in certain populations and with obesity and metabolic syndrome. Alternative splicing results in multiple transcript variants.;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.117 ng/mL

CLOCK ELISA Kit (Human) (OKEH08376)

OKEH08376 Aviva Systems Biology 96 Wells 896 EUR
Description: Description of target: The protein encoded by this gene plays a central role in the regulation of circadian rhythms. The protein encodes a transcription factor of the basic helix-loop-helix (bHLH) family and contains DNA binding histone acetyltransferase activity. The encoded protein forms a heterodimer with ARNTL (BMAL1) that binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Polymorphisms in this gene may be associated with behavioral changes in certain populations and with obesity and metabolic syndrome. Alternative splicing results in multiple transcript variants.;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.089ng/mL

Clock Cell ELISA Kit

abx595660-96tests Abbexa 96 tests 637 EUR

Mouse Clock ELISA KIT

ELI-33824m Lifescience Market 96 Tests 865 EUR

Chicken CLOCK ELISA KIT

ELI-09126c Lifescience Market 96 Tests 928 EUR

Clock Homolog (CLOCK) Polyclonal Antibody (Human)

4-PAQ116Hu01 Cloud-Clone
  • 262.00 EUR
  • 2747.00 EUR
  • 679.00 EUR
  • 331.00 EUR
  • 220.00 EUR
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Clock Homolog (CLOCK)

Clock Homolog (CLOCK) Antibody

20-abx131224 Abbexa
  • 453.00 EUR
  • 133.00 EUR
  • 1316.00 EUR
  • 620.00 EUR
  • 342.00 EUR
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Recombinant Clock Homolog (CLOCK)

4-RPQ116Hu01 Cloud-Clone
  • 454.82 EUR
  • 224.00 EUR
  • 1430.56 EUR
  • 543.52 EUR
  • 987.04 EUR
  • 367.00 EUR
  • 3426.40 EUR
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Circadian Locomoter Output Cycles Protein Kaput expressed in: E.coli

Human Period Circadian Protein 1 (PER1) ELISA Kit

20-abx152702 Abbexa
  • 7378.00 EUR
  • 3933.00 EUR
  • 911.00 EUR
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Period Circadian Protein 1 (PER1) ELISA Kit

20-abx585343 Abbexa
  • 7645.00 EUR
  • 4074.00 EUR
  • 942.00 EUR
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Period Circadian Protein 1 (PER1)ELISA kit

201-12-3257 SunredBio 96 tests 440 EUR
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Period Circadian Protein 1 ELISA Kit (PER1)

RK02058 Abclonal 96 Tests 521 EUR

Human Period Circadian Protein 1 (PER1) ELISA Kit

RDR-PER1-Hu-48Tests Reddot Biotech 48 Tests 589 EUR

Human Period Circadian Protein 1 (PER1) ELISA Kit

RDR-PER1-Hu-96Tests Reddot Biotech 96 Tests 820 EUR

Human Period Circadian Protein 1 (PER1) ELISA Kit

RD-PER1-Hu-48Tests Reddot Biotech 48 Tests 563 EUR

Human Period Circadian Protein 1 (PER1) ELISA Kit

RD-PER1-Hu-96Tests Reddot Biotech 96 Tests 783 EUR

Human Period Circadian Protein 1 (PER1) ELISA Kit

DLR-PER1-Hu-48T DL Develop 48T 554 EUR
Description: A sandwich quantitative ELISA assay kit for detection of Human Period Circadian Protein 1 (PER1) in samples from tissue homogenates, cell lysates or other biological fluids.

Human Period Circadian Protein 1 (PER1) ELISA Kit

DLR-PER1-Hu-96T DL Develop 96T 725 EUR
Description: A sandwich quantitative ELISA assay kit for detection of Human Period Circadian Protein 1 (PER1) in samples from tissue homogenates, cell lysates or other biological fluids.

Human Period Circadian Protein 1 (PER1) ELISA Kit

SEM012Hu-10x96wellstestplate Cloud-Clone 10x96-wells test plate 5189.65 EUR
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Period Circadian Protein 1 (PER1) in Tissue homogenates, cell lysates and other biological fluids.

Human Period Circadian Protein 1 (PER1) ELISA Kit

SEM012Hu-1x48wellstestplate Cloud-Clone 1x48-wells test plate 515.03 EUR
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Period Circadian Protein 1 (PER1) in Tissue homogenates, cell lysates and other biological fluids.

Human Period Circadian Protein 1 (PER1) ELISA Kit

SEM012Hu-1x96wellstestplate Cloud-Clone 1x96-wells test plate 692.9 EUR
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Period Circadian Protein 1 (PER1) in Tissue homogenates, cell lysates and other biological fluids.

Human CLOCK(Circadian Locomoter Output Cycles Protein Kaput) ELISA Kit